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Find marker genes for each annotation

Usage

find_markers(
  obj,
  top_n = 10L,
  exclude_pattern = "^(RPL|RPS|MT-|MALAT1$|MTRNR|HSP)",
  min_pct_in = 0.1,
  min_pct_diff = 0.05,
  min_marker_score = 0.25,
  outdir = NULL
)

Arguments

obj

A scdown_obj.

top_n

Number of top marker genes per annotation.

exclude_pattern

Pattern for low-information genes to exclude.

min_pct_in

Minimum detection rate inside the target annotation.

min_pct_diff

Minimum detection improvement over the rest.

min_marker_score

Minimum expression improvement over the rest.

outdir

Optional output directory.

Value

A list with marker tables and plot paths.